Instead, the AASM recommends other sleep medications, such as Belsomra (suvorexant), Lunesta (eszopiclone), or Sonata (zaleplon). The AASM task force determined that trazodone produced no significant improvement in sleep and is linked to various side effects.
#Trazodone for insomnia vs depression trial#
Trazodone guidelines from the AASM are based on a short-term clinical trial that compared 50 mg of trazodone to 10 mg of Ambien (zolpidem) and placebo. The American Academy of Sleep Medicine (AASM) recommends avoiding trazodone for chronic insomnia. However, more large-scale clinical trials are needed to evaluate these findings. In other words, trazodone can be a useful drug to help a person fall asleep faster and stay asleep throughout the night. In addition, trazodone may help improve deep sleep, or slow-wave sleep. Studies analyzed in the review found that trazodone may help improve sleep latency, duration, and quality. One systematic review compiled and analyzed various studies on trazodone for insomnia, and it concluded that low doses of trazodone could be a safe and effective way to help treat insomnia.
Primary insomnia is not caused by a medical condition or problem, while secondary insomnia typically develops due to a health condition, such as a mental health disorder, lung disease, or cancer. Some research suggests that trazodone can be an effective medication for treating primary and secondary insomnia.
Prescribing a drug off-label is up to the discretion and judgment of a healthcare provider. The use of a medication for something other than its intended FDA-approved use is called off-label use, and it is a common practice by healthcare providers. Although not approved as a sleep aid by the FDA, trazodone is sometimes prescribed for insomnia. Trazodone is not approved as a sleep aid by the Food and Drug Administration (FDA), but rather as a treatment of depression. RELATED: Get trazodone coupons | What is trazodone? Is trazodone approved as a sleep aid? Trazodone may be especially useful for people who experience insomnia caused by depression. Trazodone is a generic drug that can be purchased under the brand name Desyrel or Oleptro.Īlthough it is mainly prescribed for depression, trazodone can be prescribed off-label to treat insomnia because of its sedative properties. Trazodone is similarly effective to other antidepressants, including tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs), but it is classified as a serotonin antagonist and reuptake inhibitor (SARI). It works by regulating certain chemicals in the central nervous system (CNS), such as serotonin. Trazodone is a prescription drug FDA approved to treat individuals with depression or major depressive disorder. Is trazodone an approved sleep aid? | Trazodone dosage | Trazodone advantages | Side effects | Alternatives | FAQs Share on Facebook Facebook Logo Share on Twitter Twitter Logo Share on LinkedIn LinkedIn Logo Copy URL to clipboard Share Icon URL copied to clipboard
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